Phenotypes associated with this allele

• Allele Symbol: Dpp9^tm1.1Mdg
• Allele Name: targeted mutation 1.1, Mark D Gorrell
• Allele ID: MGI:5574450
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dpp9^tm1.1Mdg/Dpp9^tm1.1Mdg	involves: C57BL/6	MGI:5574452
ht2	Dpp9^tm1.1Mdg/Dpp9^+	involves: C57BL/6	MGI:5574455

Genotype
MGI:5574452

hm1

• Allelic Composition: Dpp9^tm1.1Mdg/Dpp9^tm1.1Mdg
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

mortality/aging ( J:209219 )

N • embryos detected up to early neonate at expected Mendelian frequency, normal gender distribution, cyanosis, breathing, food intake, behavior, skin phenotype, hydration, weight, and urine protein level

postnatal lethality, complete penetrance ( J:209219 )

• no homozygotes are found at weaning

neonatal lethality, incomplete penetrance ( J:209219 )

• gradual display of weak respiratory movements, lethargy and some die within the first 24 hours

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:209219 )

N • no urinary protein difference

Genotype
MGI:5574455

ht2

• Allelic Composition: Dpp9^tm1.1Mdg/Dpp9⁺
• Genetic Background: involves: C57BL/6

mortality/aging

neonatal lethality, incomplete penetrance ( J:209219 )

• some mice die within 24 h of birth

postnatal lethality, incomplete penetrance ( J:209219 )

• normal Mendelian frequency at birth but distribution skewed towards wild-type at weaning

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:209219 )

N • no urinary protein difference