All Phenotypes Apbb2<tm1.1(KOMP)Vlcg> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Apbb2^{tm1.1(KOMP)Vlcg}
targeted mutation 1.1, Velocigene
MGI:5574593

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Apbb2^{tm1.1(KOMP)Vlcg}/Apbb2^{tm1.1(KOMP)Vlcg}	C57BL/6N-Apbb2^{tm1.1(KOMP)Vlcg}/Ucd	MGI:5767563
ht2	Apbb2^{tm1.1(KOMP)Vlcg}/Apbb2⁺	C57BL/6N-Apbb2^{tm1.1(KOMP)Vlcg}/Ucd	MGI:5797362

Allelic Composition	Apbb2^{tm1.1(KOMP)Vlcg}/Apbb2^{tm1.1(KOMP)Vlcg}
Genetic Background	C57BL/6N-Apbb2^{tm1.1(KOMP)Vlcg}/Ucd
Cell Lines	14762A-E10

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apbb2^{tm1.1(KOMP)Vlcg} mutation (1 available); any Apbb2 mutation (66 available)

Data Sources

IMPC Data for Apbb2

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

hemorrhage ( J:211773 )

IMPC - UCD

embryo

spina bifida ( J:211773 )

IMPC - UCD

growth/size/body

microcephaly ( J:211773 )

IMPC - UCD

limbs/digits/tail

polydactyly ( J:211773 )

IMPC - UCD

syndactyly ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - UCD

nervous system

spina bifida ( J:211773 )

IMPC - UCD

vision/eye

microphthalmia ( J:211773 )

IMPC - UCD

anophthalmia ( J:211773 )

IMPC - UCD

Allelic Composition	Apbb2^{tm1.1(KOMP)Vlcg}/Apbb2⁺
Genetic Background	C57BL/6N-Apbb2^{tm1.1(KOMP)Vlcg}/Ucd
Cell Lines	14762A-E10

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apbb2^{tm1.1(KOMP)Vlcg} mutation (1 available); any Apbb2 mutation (66 available)

Data Sources

IMPC Data for Apbb2

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

hemorrhage ( J:211773 )

IMPC - UCD

embryo

spina bifida ( J:211773 )

IMPC - UCD

growth/size/body

microcephaly ( J:211773 )

IMPC - UCD

increased lung weight ( J:211773 )

IMPC - UCD

homeostasis/metabolism

increased circulating alanine transaminase level ( J:211773 )

IMPC - UCD

increased circulating aspartate transaminase level ( J:211773 )

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

IMPC - UCD

limbs/digits/tail

polydactyly ( J:211773 )

IMPC - UCD

syndactyly ( J:211773 )

IMPC - UCD

nervous system

spina bifida ( J:211773 )

IMPC - UCD

respiratory system

increased lung weight ( J:211773 )

IMPC - UCD

vision/eye

abnormal eye morphology ( J:211773 )

IMPC - UCD

microphthalmia ( J:211773 )

IMPC - UCD

anophthalmia ( J:211773 )

IMPC - UCD

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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