Phenotypes associated with this allele

• Allele Symbol: Yipf5^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5574599
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Yipf5^tm1b(EUCOMM)Hmgu/Yipf5^tm1b(EUCOMM)Hmgu	C57BL/6N-Yipf5^tm1b(EUCOMM)Hmgu/Ics	MGI:5757899
ht2	Yipf5^tm1b(EUCOMM)Hmgu/Yipf5^+	C57BL/6N-Yipf5^tm1b(EUCOMM)Hmgu/Ics	MGI:5757898

Genotype
MGI:5757899

hm1

• Allelic Composition: Yipf5^{tm1b(EUCOMM)Hmgu}/Yipf5^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Yipf5^{tm1b(EUCOMM)Hmgu}/Ics
• Cell Lines: HEPD0534_4_D04

Data Sources

IMPC Data for Yipf5

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - ICS

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - ICS

preweaning lethality, complete penetrance ( J:211773 )

IMPC - ICS

Genotype
MGI:5757898

ht2

• Allelic Composition: Yipf5^{tm1b(EUCOMM)Hmgu}/Yipf5⁺
• Genetic Background: C57BL/6N-Yipf5^{tm1b(EUCOMM)Hmgu}/Ics
• Cell Lines: HEPD0534_4_D04

Data Sources

IMPC Data for Yipf5

cardiovascular system

thick ventricular wall ( J:211773 )

♂

IMPC - ICS

hematopoietic system

decreased erythrocyte cell number ( J:211773 )

♂

IMPC - ICS

nervous system

increased prepulse inhibition ( J:211773 )

♀

IMPC - ICS

vision/eye

abnormal retina outer nuclear layer morphology ( J:211773 )

IMPC - ICS

decreased total retina thickness ( J:211773 )

♂

IMPC - ICS