Phenotypes associated with this allele

• Allele Symbol: Iah1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5574600
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Iah1^tm1b(EUCOMM)Hmgu/Iah1^tm1b(EUCOMM)Hmgu	C57BL/6N-Iah1^tm1b(EUCOMM)Hmgu/Ics	MGI:5757240
hm2	Iah1^tm1b(EUCOMM)Hmgu/Iah1^tm1b(EUCOMM)Hmgu	involves: C57BL * C57BL/6N * DBA	MGI:6456061

Genotype
MGI:5757240

hm1

• Allelic Composition: Iah1^{tm1b(EUCOMM)Hmgu}/Iah1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Iah1^{tm1b(EUCOMM)Hmgu}/Ics
• Cell Lines: HEPD0531_2_E06

Data Sources

IMPC Data for Iah1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

prolonged QT interval ( J:211773 )

♂

IMPC - ICS

prolonged ST segment ( J:211773 )

♂

IMPC - ICS

homeostasis/metabolism

decreased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - ICS

nervous system

increased prepulse inhibition ( J:211773 )

♂

IMPC - ICS

Genotype
MGI:6456061

hm2

• Allelic Composition: Iah1^{tm1b(EUCOMM)Hmgu}/Iah1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: involves: C57BL * C57BL/6N * DBA

adipose tissue

increased mesenteric fat pad weight ( J:289414 )

• however, other white adipose tissues are normal