Phenotypes associated with this allele

• Allele Symbol: Prdm10^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5574612
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prdm10^tm1b(EUCOMM)Hmgu/Prdm10^tm1b(EUCOMM)Hmgu	C57BL/6N-Prdm10^tm1b(EUCOMM)Hmgu/Ics	MGI:5757556
ht2	Prdm10^tm1b(EUCOMM)Hmgu/Prdm10^+	C57BL/6N-Prdm10^tm1b(EUCOMM)Hmgu/Ics	MGI:5757555

Genotype
MGI:5757556

hm1

• Allelic Composition: Prdm10^{tm1b(EUCOMM)Hmgu}/Prdm10^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Prdm10^{tm1b(EUCOMM)Hmgu}/Ics
• Cell Lines: HEPD0535_2_A08

Data Sources

IMPC Data for Prdm10

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - ICS

preweaning lethality, complete penetrance ( J:211773 )

IMPC - ICS

Genotype
MGI:5757555

ht2

• Allelic Composition: Prdm10^{tm1b(EUCOMM)Hmgu}/Prdm10⁺
• Genetic Background: C57BL/6N-Prdm10^{tm1b(EUCOMM)Hmgu}/Ics
• Cell Lines: HEPD0535_2_A08

Data Sources

IMPC Data for Prdm10

adipose tissue

decreased total body fat amount ( J:211773 )

♂

IMPC - ICS

behavior/neurological

decreased grip strength ( J:211773 )

♂

IMPC - ICS

growth/size/body

increased lean body mass ( J:211773 )

♂

IMPC - ICS

skeleton

decreased bone mineral content ( J:211773 )

♂

IMPC - ICS