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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Cxcl12tm1.1Fass
targeted mutation 1.1, Fernando Arenzana-Seisdedos
MGI:5575859
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Cxcl12tm1.1Fass/Cxcl12tm1.1Fass involves: 129S6/SvEvTac * C57BL/6NTac MGI:5575865


Genotype
MGI:5575865
hm1
Allelic
Composition
Cxcl12tm1.1Fass/Cxcl12tm1.1Fass
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cxcl12tm1.1Fass mutation (0 available); any Cxcl12 mutation (25 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• reduced paw perfusion in ischemic hind limb with reduced vessel density
• reduced capillary and arteriole vessel regeneration with reduced numbers of macrophages following postischemic freezing of the calf muscle





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory