craniofacial
• the molars of transgenic mice erupt later than those of wild-type mice.
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growth/size/body
• the molars of transgenic mice erupt later than those of wild-type mice.
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immune system
• transgenic mice exhibit decreased myeloid cell numbers.
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integument
• transgenic mice exhibit premature greying of coat hair.
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pigmentation
• transgenic mice exhibit premature greying of coat hair.
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reproductive system
• female mice hemizygous for this transgene exhibit very low fertility, so that all breeding of the line has employed wild-type females and hemizygous transgenic males.
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skeleton
• the molars of transgenic mice erupt later than those of wild-type mice.
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