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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Cd68-BCL2)533Medz
transgene insertion 533, Ruslan Medzhitov
MGI:5576387
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Cd68-BCL2)533Medz/0 involves: 129 * C57BL/6 MGI:5576389


Genotype
MGI:5576389
tg1
Allelic
Composition
Tg(Cd68-BCL2)533Medz/0
Genetic
Background
involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Cd68-BCL2)533Medz mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• the molars of transgenic mice erupt later than those of wild-type mice.

growth/size/body
• the molars of transgenic mice erupt later than those of wild-type mice.

immune system
• transgenic mice exhibit decreased myeloid cell numbers.

integument
• transgenic mice exhibit premature greying of coat hair.

pigmentation
• transgenic mice exhibit premature greying of coat hair.

reproductive system
• female mice hemizygous for this transgene exhibit very low fertility, so that all breeding of the line has employed wild-type females and hemizygous transgenic males.

skeleton
• the molars of transgenic mice erupt later than those of wild-type mice.





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory