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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(n-TRtct5)609Slac
transgene insertion 609, Susan L Ackerman
MGI:5576567
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Gtpbp2nmf205/Gtpbp2nmf205
Tg(n-TRtct5)609Slac/0 		C57BL/6J-Gtpbp2nmf205 Tg(n-TRtct5)609Slac MGI:5577075


Genotype
MGI:5577075
cx1
Allelic
Composition		 Gtpbp2nmf205/Gtpbp2nmf205
Tg(n-TRtct5)609Slac/0
Genetic
Background		 C57BL/6J-Gtpbp2nmf205 Tg(n-TRtct5)609Slac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gtpbp2nmf205 mutation (1 available); any Gtpbp2 mutation (38 available)
Tg(n-TRtct5)609Slac mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal cerebellum morphology ( J:211326 )
• although the cerebellum is not identical to Gtpbp2 wild-type controls, this transgene, which has brain-specific expression of wild-type n-Tr20, rescues most of the nmf205 mutant phenotype such that at 6 months of age the neuronal death is greatly attenuated in the brain and retina




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory