Phenotypes associated with this allele

• Allele Symbol: Cep19^tm2.1Jmgi
• Allele Name: targeted mutation 2.1, John Martignetti
• Allele ID: MGI:5576738
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cep19^tm2.1Jmgi/Cep19^tm2.1Jmgi	involves: C57BL/6NTac	MGI:5576750

Genotype
MGI:5576750

hm1

• Allelic Composition: Cep19^tm2.1Jmgi/Cep19^tm2.1Jmgi
• Genetic Background: involves: C57BL/6NTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

increased body weight ( J:206667 )

• at 8 and 13 weeks, respectively, in male and female mice

obese ( J:206667 )

increased body length ( J:206667 )

homeostasis/metabolism

increased circulating glucose level ( J:206667 )

♂ • in male mice and a less pronounced trend in female mice

increased circulating triglyceride level ( J:206667 )

• in female mice at 7 and 16 weeks

• mild in male mice at 7 weeks, but not 16 weeks

impaired glucose tolerance ( J:206667 )

• in male mice and less pronounced in female mice

insulin resistance ( J:206667 )

• intraperitoneal insulin resistance in female and male mice

adipose tissue

increased total body fat amount ( J:206667 )

• 2-fold increase

increased percent body fat/body weight ( J:206667 )

• 2-fold increase