Analysis Tools
mortality/aging
|
• fewer than expected mice are present at weaning with only a few mice dying after birth
|
behavior/neurological
| N |
• mice exhibit normal vertical exploratory activity (rearings)
|
|
• in the hole-board test, female mice exhibit increased number of unexplored squares and a tendency for defecation compared with control mice
• male, but not female, mice exhibit increased time in the open arms of a plus maze compared with control mice
• in a plus maze, mice exhibit fewer numbers of entry into the closed arms and reduced time in the center compared with control mice
|
 |
• male, but not female, mice exhibit increased number of head dips and time spent dipping their head in the hole-board test compared with control mice
|
|
• decreased ambulation in the hole-board test, especially in female mice
|
growth/size/body
|
|
• in male, but not female, mice
|
nervous system
microgliosis
(
J:211914
)
|
• in the cerebellum of male and female mice
• in the hippocampus and cortex of male mice
|
immune system
microgliosis
(
J:211914
)
|
• in the cerebellum of male and female mice
• in the hippocampus and cortex of male mice
|
hematopoietic system
microgliosis
(
J:211914
)
|
• in the cerebellum of male and female mice
• in the hippocampus and cortex of male mice
|
