All Phenotypes Fasl<m1Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fasl^m1Btlr
mutation 1, Bruce Beutler
MGI:5578030

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fasl^m1Btlr/Fasl^m1Btlr	C57BL/6J-Fasl^m1Btlr	MGI:5578041

Allelic Composition	Fasl^m1Btlr/Fasl^m1Btlr
Genetic Background	C57BL/6J-Fasl^m1Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fasl^m1Btlr mutation (1 available); any Fasl mutation (37 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal humoral immune response ( J:212067 )

• mice lack a T-dependent IgG response to a model antigen encoded by a replication deficient rSFV vector

• one mouse exhibited decrease T-independent IgM response to NP-Ficoll

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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