mortality/aging
• mice infected with Salmonella Typhimurium exhibit increased lethality compared with wild-type mice
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immune system
• in mice infected with Salmonella Typhimurium
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• in mice infected with Salmonella Typhimurium
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• from splenocytes stimulated with IL12
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• mice infected with Salmonella Typhimurium exhibit increased lethality, impaired systemic IFN-gamma secretion, fewer and smaller microabscess in the liver and increased bacterial burden in the spleen (17.2-fold) and liver (87.3-fold) compared with wild-type mice
• 4 days after Salmonella infection, mice exhibit less submucosal edema, less PMN cell infiltration of the lamina propria, increased goblet cells count and decreased epithelial integrity compared with wild-type mice
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• mice infected with Salmonella Typhimurium exhibit increased lethality compared with wild-type mice
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homeostasis/metabolism
• in mice infected with Salmonella Typhimurium
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• in mice infected with Salmonella Typhimurium
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