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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Grid2ho-19J
hotfoot 19 Jackson
MGI:5578546
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Grid2ho-19J/Grid2ho-19J C57BL/6J-Grid2ho-19J/GrsrJ MGI:5578623


Genotype
MGI:5578623
hm1
Allelic
Composition
Grid2ho-19J/Grid2ho-19J
Genetic
Background
C57BL/6J-Grid2ho-19J/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grid2ho-19J mutation (1 available); any Grid2 mutation (85 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• by 3 weeks of age all homozygotes display a rear-leg high-stepping ataxia typical of hotfoot mutants, wherein the rear legs are each lifted higher than normal and placed down with a patting-like motion, and by approximately 2 weeks of age some homozygotes display a leaning, side-to-side gait

growth/size/body
• by 2 weeks of age some homozygotes have a slightly smaller body size





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory