Phenotypes associated with this allele

• Allele Symbol: Tmprss2^{tm1.1(ERG)Sho}
• Allele Name: targeted mutation 1.1, Stuart Orkin
• Allele ID: MGI:5578606
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tmprss2^tm1.1(ERG)Sho/Tmprss2^tm1.1(ERG)Sho	involves: C57BL/6 * DBA/2	MGI:5578645
cx2	Pten^tm1.1Hwu/Pten^+ Tmprss2^tm1.1(ERG)Sho/Tmprss2^tm1.1(ERG)Sho	involves: 129S4/SvJae * C57BL/6 * DBA/2	MGI:5578646

Genotype
MGI:5578645

hm1

• Allelic Composition: Tmprss2^{tm1.1(ERG)Sho}/Tmprss2^{tm1.1(ERG)Sho}
• Genetic Background: involves: C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:212219 )

♂N • prostates are largely normal and do not develop prostatic intraepithelial neoplasia (PIN) lesions or cancer

♂N • prostate cell testosterone levels are normal in castrated and non-castrated mice

neoplasm

neoplasm ( J:212219 )

♂N • prostates are largely normal and do not develop prostatic intraepithelial neoplasia (PIN) lesions or cancer

Genotype
MGI:5578646

cx2

• Allelic Composition: Pten^tm1.1Hwu/Pten⁺; Tmprss2^{tm1.1(ERG)Sho}/Tmprss2^{tm1.1(ERG)Sho}
• Genetic Background: involves: 129S4/SvJae * C57BL/6 * DBA/2

neoplasm

increased prostate intraepithelial neoplasia incidence ( J:212219 )

♂

reproductive system

increased prostate intraepithelial neoplasia incidence ( J:212219 )

♂

endocrine/exocrine glands

increased prostate intraepithelial neoplasia incidence ( J:212219 )

♂