About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tmprss2tm3Sho
targeted mutation 3, Stuart Orkin
MGI:5578610
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Ergtm1.1Sho/Ergtm1.1Sho
Ptentm1Hwu/Ptentm1Hwu
Tmprss2tm3Sho/Tmprss2tm3Sho
Tg(Pbsn-cre)4Prb/0 		involves: 129S4/SvJae * C57BL/6 * DBA/2 MGI:5578652


Genotype
MGI:5578652
cn1
Allelic
Composition		 Ergtm1.1Sho/Ergtm1.1Sho
Ptentm1Hwu/Ptentm1Hwu
Tmprss2tm3Sho/Tmprss2tm3Sho
Tg(Pbsn-cre)4Prb/0
Genetic
Background		 involves: 129S4/SvJae * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ergtm1.1Sho mutation (0 available); any Erg mutation (27 available)
Ptentm1Hwu mutation (16 available); any Pten mutation (89 available)
Tg(Pbsn-cre)4Prb mutation (2 available)
Tmprss2tm3Sho mutation (0 available); any Tmprss2 mutation (56 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
increased prostate gland adenocarcinoma incidence ( J:212219 )
• regions of invasive prostate adenocarcinoma in mice over 1 year of age

mortality/aging
mortality/aging ( J:212219 )
N
• mice survive at least 1 year

neoplasm
increased prostate gland adenocarcinoma incidence ( J:212219 )
• regions of invasive prostate adenocarcinoma in mice over 1 year of age

reproductive system
increased prostate gland adenocarcinoma incidence ( J:212219 )
• regions of invasive prostate adenocarcinoma in mice over 1 year of age




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory