Phenotypes associated with this allele

• Allele Symbol: Del(16Tmprss2-Erg)1Sho
• Allele Name: deletion, Chr 16, Stuart Orkin 1
• Allele ID: MGI:5578624
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Del(16Tmprss2-Erg)1Sho/Del(16Tmprss2-Erg)1Sho	involves: C57BL/6 * DBA/2	MGI:5578650
cx2	Del(16Tmprss2-Erg)1Sho/Del(16Tmprss2-Erg)1Sho Pten^tm1.1Hwu/Pten^+	involves: 129S4/SvJae * C57BL/6 * DBA/2	MGI:5578651

Genotype
MGI:5578650

hm1

• Allelic Composition: Del(16Tmprss2-Erg)1Sho/Del(16Tmprss2-Erg)1Sho
• Genetic Background: involves: C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

prostate gland hyperplasia ( J:212219 )

♂ • 4 of 21 mice exhibit some hyperplasia and foci of cells with lightly stained cytoplasm and loss of polarity

neoplasm

neoplasm ( J:212219 )

♂N • prostates are largely normal and do not develop prostatic intraepithelial neoplasia (PIN) lesions or cancer

endocrine/exocrine glands

prostate gland hyperplasia ( J:212219 )

♂ • 4 of 21 mice exhibit some hyperplasia and foci of cells with lightly stained cytoplasm and loss of polarity

Genotype
MGI:5578651

cx2

• Allelic Composition: Del(16Tmprss2-Erg)1Sho/Del(16Tmprss2-Erg)1Sho; Pten^tm1.1Hwu/Pten⁺
• Genetic Background: involves: 129S4/SvJae * C57BL/6 * DBA/2

neoplasm

increased prostate intraepithelial neoplasia incidence ( J:212219 )

♂

endocrine/exocrine glands

increased prostate intraepithelial neoplasia incidence ( J:212219 )

♂

reproductive system

increased prostate intraepithelial neoplasia incidence ( J:212219 )

♂