Phenotypes associated with this allele

• Allele Symbol: Slc39a5^tm1.1Gka
• Allele Name: targeted mutation 1.1, Glen K Andrews
• Allele ID: MGI:5581453
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc39a5^tm1.1Gka/Slc39a5^tm1.1Gka	involves: 129P2/OlaHsd * C57BL/6 * FVB/N	MGI:5581457

Genotype
MGI:5581457

hm1

• Allelic Composition: Slc39a5^tm1.1Gka/Slc39a5^tm1.1Gka
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal zinc homeostasis ( J:209760 )

• mice fed excess zinc fail to exhibit an increase in pancreas zinc levels unlike wild-type mice

• mice exhibit increased susceptibility to zinc-induced pancreatitis compared with control mice

abnormal liver zinc level ( J:209760 )

• increased

endocrine/exocrine glands

pancreatic acinar cell atrophy ( J:209760 )

• in mice exposed to zinc

increased susceptibility to induced pancreatitis ( J:209760 )

• mice exhibit increased susceptibility to zinc-induced pancreatitis compared with control mice

liver/biliary system

abnormal liver zinc level ( J:209760 )

• increased

immune system

increased susceptibility to induced pancreatitis ( J:209760 )

• mice exhibit increased susceptibility to zinc-induced pancreatitis compared with control mice

digestive/alimentary system

pancreatic acinar cell atrophy ( J:209760 )

• in mice exposed to zinc