Phenotypes associated with this allele

• Allele Symbol: Spin1^{tm1.1(KOMP)Vlcg}
• Allele Name: targeted mutation 1.1, Velocigene
• Allele ID: MGI:5581470
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Spin1^tm1.1(KOMP)Vlcg/Spin1^tm1.1(KOMP)Vlcg	C57BL/6N-Spin1^tm1.1(KOMP)Vlcg/J	MGI:6263559
ht2	Spin1^tm1.1(KOMP)Vlcg/Spin1^+	C57BL/6N-Spin1^tm1.1(KOMP)Vlcg/J	MGI:6263558

Genotype
MGI:6263559

hm1

• Allelic Composition: Spin1^{tm1.1(KOMP)Vlcg}/Spin1^{tm1.1(KOMP)Vlcg}
• Genetic Background: C57BL/6N-Spin1^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 17512A-B7

Data Sources

IMPC Data for Spin1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:6263558

ht2

• Allelic Composition: Spin1^{tm1.1(KOMP)Vlcg}/Spin1⁺
• Genetic Background: C57BL/6N-Spin1^{tm1.1(KOMP)Vlcg}/J
• Cell Lines: 17512A-B7

Data Sources

IMPC Data for Spin1

behavior/neurological

increased startle reflex ( J:211773 )

♂

IMPC - JAX

hyperactivity ( J:211773 )

IMPC - JAX

increased vertical activity ( J:211773 )

IMPC - JAX

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - JAX

nervous system

abnormal optic disk morphology ( J:211773 )

♀

IMPC - JAX

vision/eye

abnormal optic disk morphology ( J:211773 )

♀

IMPC - JAX

persistence of hyaloid vascular system ( J:211773 )

IMPC - JAX