All Phenotypes Piezo1<tm1b(KOMP)Wtsi> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Piezo1^{tm1b(KOMP)Wtsi}
targeted mutation 1b, Wellcome Trust Sanger Institute
MGI:5582446

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Piezo1^{tm1b(KOMP)Wtsi}/Piezo1^{tm1b(KOMP)Wtsi}	C57BL/6N-Piezo1^{tm1b(KOMP)Wtsi}/MbpMmucd	MGI:6325166
hm2	Piezo1^{tm1b(KOMP)Wtsi}/Piezo1^{tm1b(KOMP)Wtsi}	C57BL/6N-Piezo1^{tm1b(KOMP)Wtsi}/Ucd	MGI:5767759
ht3	Piezo1^{tm1b(KOMP)Wtsi}/Piezo1⁺	C57BL/6N-Piezo1^{tm1b(KOMP)Wtsi}/MbpMmucd	MGI:6325165
ht4	Piezo1^{tm1b(KOMP)Wtsi}/Piezo1⁺	C57BL/6N-Piezo1^{tm1b(KOMP)Wtsi}/Ucd	MGI:6263160

Allelic Composition	Piezo1^{tm1b(KOMP)Wtsi}/Piezo1^{tm1b(KOMP)Wtsi}
Genetic Background	C57BL/6N-Piezo1^{tm1b(KOMP)Wtsi}/MbpMmucd
Cell Lines	EPD0500_5_B12

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Piezo1^{tm1b(KOMP)Wtsi} mutation (1 available); any Piezo1 mutation (89 available)

Data Sources

IMPC Data for Piezo1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

embryonic growth retardation ( J:211773 )

IMPC - TCP

abnormal embryo size ( J:211773 )

IMPC - TCP

abnormal limb bud morphology ( J:211773 )

IMPC - TCP

abnormal placenta size ( J:211773 )

IMPC - TCP

pale yolk sac ( J:211773 )

IMPC - TCP

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - TCP

abnormal embryo size ( J:211773 )

IMPC - TCP

integument

pallor ( J:211773 )

IMPC - TCP

limbs/digits/tail

abnormal limb bud morphology ( J:211773 )

IMPC - TCP

Allelic Composition	Piezo1^{tm1b(KOMP)Wtsi}/Piezo1^{tm1b(KOMP)Wtsi}
Genetic Background	C57BL/6N-Piezo1^{tm1b(KOMP)Wtsi}/Ucd
Cell Lines	EPD0500_5_B12

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Piezo1^{tm1b(KOMP)Wtsi} mutation (1 available); any Piezo1 mutation (89 available)

Data Sources

IMPC Data for Piezo1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

Allelic Composition	Piezo1^{tm1b(KOMP)Wtsi}/Piezo1⁺
Genetic Background	C57BL/6N-Piezo1^{tm1b(KOMP)Wtsi}/MbpMmucd
Cell Lines	EPD0500_5_B12

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Piezo1^{tm1b(KOMP)Wtsi} mutation (1 available); any Piezo1 mutation (89 available)

Data Sources

IMPC Data for Piezo1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal embryo size ( J:211773 )

IMPC - TCP

abnormal placenta size ( J:211773 )

IMPC - TCP

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - TCP

Allelic Composition	Piezo1^{tm1b(KOMP)Wtsi}/Piezo1⁺
Genetic Background	C57BL/6N-Piezo1^{tm1b(KOMP)Wtsi}/Ucd
Cell Lines	EPD0500_5_B12

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Piezo1^{tm1b(KOMP)Wtsi} mutation (1 available); any Piezo1 mutation (89 available)

Data Sources

IMPC Data for Piezo1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased locomotor activity ( J:211773 )

IMPC - UCD

homeostasis/metabolism

increased circulating alanine transaminase level ( J:211773 )

IMPC - UCD

renal/urinary system

abnormal urinary bladder morphology ( J:211773 )

IMPC - UCD

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24