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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Map3k8m2Btlr
mutation 2, Bruce Beutler
MGI:5582496
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Map3k8m2Btlr/Map3k8m2Btlr C57BL/6J-Map3k8m2Btlr MGI:5582502


Genotype
MGI:5582502
hm1
Allelic
Composition		 Map3k8m2Btlr/Map3k8m2Btlr
Genetic
Background		 C57BL/6J-Map3k8m2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map3k8m2Btlr mutation (0 available); any Map3k8 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal response to infection ( J:212899 )
• some mice showed diminished LPS-induced TNFalpha secretion




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory