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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Anpeptm1Afk
targeted mutation 1, Andreas Kolb
MGI:5582781
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Anpeptm1Afk/Anpeptm1Afk B6.129-Anpeptm1Afk MGI:5582785
hm2
 		Anpeptm1Afk/Anpeptm1Afk involves: 129/Sv * C57BL/6J MGI:5582784


Genotype
MGI:5582785
hm1
Allelic
Composition		 Anpeptm1Afk/Anpeptm1Afk
Genetic
Background		 B6.129-Anpeptm1Afk
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Anpeptm1Afk mutation (2 available); any Anpep mutation (84 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
impaired mammary gland growth during pregnancy ( J:212511 )
• fewer buds, reduced side branch junctions and increased distance between side branches at day 10 and 15 of gestation
• however, mice lactate normally

integument
impaired mammary gland growth during pregnancy ( J:212511 )
• fewer buds, reduced side branch junctions and increased distance between side branches at day 10 and 15 of gestation
• however, mice lactate normally

reproductive system
impaired mammary gland growth during pregnancy ( J:212511 )
• fewer buds, reduced side branch junctions and increased distance between side branches at day 10 and 15 of gestation
• however, mice lactate normally




Genotype
MGI:5582784
hm2
Allelic
Composition		 Anpeptm1Afk/Anpeptm1Afk
Genetic
Background		 involves: 129/Sv * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Anpeptm1Afk mutation (2 available); any Anpep mutation (84 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
impaired mammary gland growth during pregnancy ( J:212511 )
• fewer buds, reduced side branch junctions and increased distance between side branches at day 10 and 15 of gestation
• however, mice lactate normally

integument
impaired mammary gland growth during pregnancy ( J:212511 )
• fewer buds, reduced side branch junctions and increased distance between side branches at day 10 and 15 of gestation
• however, mice lactate normally

reproductive system
impaired mammary gland growth during pregnancy ( J:212511 )
• fewer buds, reduced side branch junctions and increased distance between side branches at day 10 and 15 of gestation
• however, mice lactate normally




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory