Phenotypes associated with this allele

• Allele Symbol: Mettl16^{tm1b(KOMP)Mbp}
• Allele Name: targeted mutation 1b, Mouse Biology Program, UC Davis
• Allele ID: MGI:5583061
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mettl16^tm1b(KOMP)Mbp/Mettl16^tm1b(KOMP)Mbp	C57BL/6N-Mettl16^tm1b(KOMP)Mbp/J	MGI:5757360
ht2	Mettl16^tm1b(KOMP)Mbp/Mettl16^+	C57BL/6N-Mettl16^tm1b(KOMP)Mbp/J	MGI:5757359

Genotype
MGI:5757360

hm1

• Allelic Composition: Mettl16^{tm1b(KOMP)Mbp}/Mettl16^{tm1b(KOMP)Mbp}
• Genetic Background: C57BL/6N-Mettl16^{tm1b(KOMP)Mbp}/J
• Cell Lines: DEPD00539_6_E09

Data Sources

IMPC Data for Mettl16

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - JAX

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:5757359

ht2

• Allelic Composition: Mettl16^{tm1b(KOMP)Mbp}/Mettl16⁺
• Genetic Background: C57BL/6N-Mettl16^{tm1b(KOMP)Mbp}/J
• Cell Lines: DEPD00539_6_E09

Data Sources

IMPC Data for Mettl16

hematopoietic system

decreased erythrocyte cell number ( J:211773 )

♂

IMPC - JAX

decreased hematocrit ( J:211773 )

♂

IMPC - JAX

decreased hemoglobin content ( J:211773 )

♂

IMPC - JAX

homeostasis/metabolism

decreased urine creatinine level ( J:211773 )

IMPC - JAX

increased circulating cholesterol level ( J:211773 )

♂

IMPC - JAX

increased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - JAX

integument

abnormal coat/hair pigmentation ( J:211773 )

♀

IMPC - JAX

pigmentation

abnormal coat/hair pigmentation ( J:211773 )

♀

IMPC - JAX

renal/urinary system

decreased urine creatinine level ( J:211773 )

IMPC - JAX