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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rhbdf2M2Btlr
mutation 2, Bruce Beutler
MGI:5583871
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Rhbdf2M2Btlr/Rhbdf2+ C57BL/6J-Rhbdf2M2Btlr MGI:5583875


Genotype
MGI:5583875
ht1
Allelic
Composition		 Rhbdf2M2Btlr/Rhbdf2+
Genetic
Background		 C57BL/6J-Rhbdf2M2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhbdf2M2Btlr mutation (1 available); any Rhbdf2 mutation (84 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal immune system physiology ( J:213194 )
• some mice exhibited decreased TNFalpha secretion in response to the Toll-like receptor (TLR) ligands LPS (TLR4), Pam3CSK4 (TLR1/2) and R848 (TLR7/8)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory