About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dseltm1Mmac
targeted mutation 1, Marco Maccarana
MGI:5583872
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dseltm1Mmac/Dseltm1Mmac involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:5583880


Genotype
MGI:5583880
hm1
Allelic
Composition		 Dseltm1Mmac/Dseltm1Mmac
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dseltm1Mmac mutation (1 available); any Dsel mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal mineral level ( J:213195 )
• reduced iduronic acid content in the brain and kidney chondroitin sulfate/dermatan sulfate (CS/DS)
abnormal enzyme/coenzyme activity ( J:213195 )
• reduced epimerase activity in the skin, lung, liver, spleen, kidney and brain

nervous system
nervous system phenotype ( J:213195 )
N
• brains exhibit normal extracellular matrix




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory