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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Etn3tm1.1Jwi
targeted mutation 1.1, Jeffrey W Innis
MGI:5584119
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Etn3tm1.1Jwi/Etn3+ involves: C57BL/6 MGI:5584141
ht2
 		Etn3tm1.1Jwi/Etn3+ involves: C57BL/6 * DBA/2 MGI:5584142
ht3
 		Etn3tm1.1Jwi/Etn3+ involves: C57BL/6 * FVB MGI:5584143


Genotype
MGI:5584141
ht1
Allelic
Composition		 Etn3tm1.1Jwi/Etn3+
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Etn3tm1.1Jwi mutation (1 available); any Etn3 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
abnormal limb development ( J:207896 )
• ectopic legs

skeleton
abnormal skeleton development ( J:207896 )
• caudal malformation




Genotype
MGI:5584142
ht2
Allelic
Composition		 Etn3tm1.1Jwi/Etn3+
Genetic
Background		 involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Etn3tm1.1Jwi mutation (1 available); any Etn3 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Characteristic caudal mass/ectopic limb phenotypes in Etn3tm2.1Jwi/Etn3+ mice

limbs/digits/tail
abnormal limb development ( J:207896 )
• ectopic legs

skeleton
abnormal skeleton development ( J:207896 )
• caudal malformation




Genotype
MGI:5584143
ht3
Allelic
Composition		 Etn3tm1.1Jwi/Etn3+
Genetic
Background		 involves: C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Etn3tm1.1Jwi mutation (1 available); any Etn3 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Characteristic caudal mass/ectopic limb phenotypes in Etn3tm2.1Jwi/Etn3+ mice

limbs/digits/tail
abnormal limb development ( J:207896 )
• ectopic legs

skeleton
abnormal skeleton development ( J:207896 )
• caudal malformation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory