Phenotypes associated with this allele

• Allele Symbol: Vezt^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5585593
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Vezt^tm1b(EUCOMM)Hmgu/Vezt^tm1b(EUCOMM)Hmgu	C57BL/6N-Vezt^tm1b(EUCOMM)Hmgu/J	MGI:5757874
ht2	Vezt^tm1b(EUCOMM)Hmgu/Vezt^+	C57BL/6N-Vezt^tm1b(EUCOMM)Hmgu/J	MGI:5757873

Genotype
MGI:5757874

hm1

• Allelic Composition: Vezt^{tm1b(EUCOMM)Hmgu}/Vezt^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Vezt^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0611_4_F08

Data Sources

IMPC Data for Vezt

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:5757873

ht2

• Allelic Composition: Vezt^{tm1b(EUCOMM)Hmgu}/Vezt⁺
• Genetic Background: C57BL/6N-Vezt^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0611_4_F08

Data Sources

IMPC Data for Vezt

behavior/neurological

decreased vertical activity ( J:211773 )

IMPC - JAX

decreased locomotor activity ( J:211773 )

IMPC - JAX

hematopoietic system

increased mean corpuscular volume ( J:211773 )

♂

IMPC - JAX

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

IMPC - JAX

increased urine microalbumin level ( J:211773 )

♀

IMPC - JAX

integument

abnormal coat appearance ( J:211773 )

IMPC - JAX

renal/urinary system

increased urine microalbumin level ( J:211773 )

♀

IMPC - JAX