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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Col1a1tm4(tetO-Jun/Fosl2)Wag
targeted mutation 4, Erwin F Wagner
MGI:5586533
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Col1a1tm4(tetO-Jun/Fosl2)Wag/Col1a1+
Tg(Cebpb-tTA)5Bjd/0 		involves: 129S4/SvJae * C57BL/6 * NMRI MGI:5586552


Genotype
MGI:5586552
cx1
Allelic
Composition		 Col1a1tm4(tetO-Jun/Fosl2)Wag/Col1a1+
Tg(Cebpb-tTA)5Bjd/0
Genetic
Background		 involves: 129S4/SvJae * C57BL/6 * NMRI
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col1a1tm4(tetO-Jun/Fosl2)Wag mutation (0 available); any Col1a1 mutation (163 available)
Tg(Cebpb-tTA)5Bjd mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
liver/biliary system
decreased liver triglyceride level ( J:210545 )
• compared with control mice when fed a high fat diet
decreased susceptibility to diet-induced hepatic steatosis ( J:210545 )
• mice fed a high fat diet do not develop steatohepatitis unlike control mice

homeostasis/metabolism
decreased liver triglyceride level ( J:210545 )
• compared with control mice when fed a high fat diet




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory