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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Snapintm2Zhs
targeted mutation 2, Zu-Hang Sheng
MGI:5586701
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Snapintm2Zhs/Snapintm2Zhs
Tg(Thy1-cre)703Vaw/0 		involves: C3H * C57BL/6 MGI:5586706


Genotype
MGI:5586706
cn1
Allelic
Composition		 Snapintm2Zhs/Snapintm2Zhs
Tg(Thy1-cre)703Vaw/0
Genetic
Background		 involves: C3H * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Snapintm2Zhs mutation (0 available); any Snapin mutation (13 available)
Tg(Thy1-cre)703Vaw mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal axonal transport ( J:207508 )
• impaired BACE1 retrograde transport
• however, anterograde transport is normal and re-introduction of HA-Snapin rescues retrograde transport




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory