Phenotypes associated with this allele

• Allele Symbol: Gba1^tm2.1Eginn
• Allele Name: targeted mutation 2.1, Edward I Ginns
• Allele ID: MGI:5587918
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gba1^tm2.1Eginn/Gba1^tm2.1Eginn	involves: 129X1/SvJ * C57BL/6	MGI:5587928

Genotype
MGI:5587928

hm1

• Allelic Composition: Gba1^tm2.1Eginn/Gba1^tm2.1Eginn
• Genetic Background: involves: 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal enzyme/coenzyme activity ( J:211953 )

• lower enzymatic in liver and spleen, 35% and 13%, respectively, compared to controls

nervous system

abnormal striatum morphology ( J:211953 )

• astrocytosis and alpha-synuclein accumulation in striatum at 1 year of age

astrocytosis ( J:211953 )

• in striatum at 1 year of age

alpha-synuclein inclusion body ( J:211953 )

• in striatum at 1 year of age