Phenotypes associated with this allele

• Allele Symbol: Atp5mc2^{tm2b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 2b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5588276
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Atp5mc2^tm2b(EUCOMM)Hmgu/Atp5mc2^tm2b(EUCOMM)Hmgu	C57BL/6N-Atp5mc2^tm2b(EUCOMM)Hmgu/Ieg	MGI:5756755
ht2	Atp5mc2^tm2b(EUCOMM)Hmgu/Atp5mc2^+	C57BL/6N-Atp5mc2^tm2b(EUCOMM)Hmgu/Ieg	MGI:5756754

Genotype
MGI:5756755

hm1

• Allelic Composition: Atp5mc2^{tm2b(EUCOMM)Hmgu}/Atp5mc2^{tm2b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Atp5mc2^{tm2b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0781_2_B02

Data Sources

IMPC Data for Atp5mc2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:5756754

ht2

• Allelic Composition: Atp5mc2^{tm2b(EUCOMM)Hmgu}/Atp5mc2⁺
• Genetic Background: C57BL/6N-Atp5mc2^{tm2b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0781_2_B02

Data Sources

IMPC Data for Atp5mc2

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

♂

IMPC - HMGU

vision/eye

abnormal lens morphology ( J:211773 )

IMPC - HMGU

abnormal retina morphology ( J:211773 )

♂

IMPC - HMGU

abnormal retina vasculature morphology ( J:211773 )

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

IMPC - HMGU

decreased total retina thickness ( J:211773 )

IMPC - HMGU