Phenotypes associated with this allele

• Allele Symbol: Syk^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5588292
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Syk^tm1b(EUCOMM)Hmgu/Syk^tm1b(EUCOMM)Hmgu	C57BL/6N-Syk^tm1b(EUCOMM)Hmgu/Ieg	MGI:6263620
ht2	Syk^tm1b(EUCOMM)Hmgu/Syk^+	C57BL/6N-Syk^tm1b(EUCOMM)Hmgu/Ieg	MGI:6263619

Genotype
MGI:6263620

hm1

• Allelic Composition: Syk^{tm1b(EUCOMM)Hmgu}/Syk^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Syk^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0722_4_A07

Data Sources

IMPC Data for Syk

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:6263619

ht2

• Allelic Composition: Syk^{tm1b(EUCOMM)Hmgu}/Syk⁺
• Genetic Background: C57BL/6N-Syk^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0722_4_A07

Data Sources

IMPC Data for Syk

adipose tissue

increased total body fat amount ( J:211773 )

IMPC - HMGU

behavior/neurological

decreased exploration in new environment ( J:211773 )

♂

IMPC - HMGU

decreased grip strength ( J:211773 )

IMPC - HMGU

growth/size/body

decreased lean body mass ( J:211773 )

IMPC - HMGU