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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Skint1m1Tac
mutation 1, Taconic
MGI:5588374
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Skint1m1Tac/Skint1m1Tac FVB/NTac MGI:5588376


Genotype
MGI:5588376
hm1
Allelic
Composition
Skint1m1Tac/Skint1m1Tac
Genetic
Background
FVB/NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Skint1m1Tac mutation (0 available); any Skint1 mutation (35 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• reduced Vgamma5+Vdelta1+ T cells due to a loss of positive selection
• however, expression of the wild-type gene via transgenic insertion rescues phenotype
• reduced Vgamma5+Vdelta1+ T cells due to a loss of positive selection
• however, expression of the wild-type gene via transgenic insertion rescues phenotype

hematopoietic system
• reduced Vgamma5+Vdelta1+ T cells due to a loss of positive selection
• however, expression of the wild-type gene via transgenic insertion rescues phenotype
• reduced Vgamma5+Vdelta1+ T cells due to a loss of positive selection
• however, expression of the wild-type gene via transgenic insertion rescues phenotype





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory