Analysis Tools|
Allele Symbol Allele Name Allele ID |
Tshz1tm1Garr targeted mutation 1, Alistair N Garratt MGI:5588813 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• homozygous mutant animals were born at the expected Mendelian frequency, but died within the first day after birth
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• contained air in their gastrointestinal tract
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mutant animals were born at the expected Mendelian frequency, but died within the first day after birth
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• in E18.5 embryo
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• approx. 70% died during the first four postnatal weeks
• mutant mice could suckle and survive during the early postnatal period
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• mutants weighed around half that of their littermates
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• a substantial reduction in the number of GABAergic cells
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/09/2024 MGI 6.24 |
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