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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Adamts9tm1.1Apte
targeted mutation 1.1, Suneel Apte
MGI:5603199
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Adamts9tm1.1Apte/Adamts9tm1.1Apte involves: C57BL/6 * SJL MGI:5603200
cn2
 		Adamts5tm1Dgen/Adamts5tm1Dgen
Adamts9tm1.1Apte/Adamts9tm1.1Apte
Tg(Prrx1-cre)1Cjt/0 		involves: 129P2/OlaHsd * C57BL/6 * SJL MGI:5603313
cn3
 		Adamts9tm1.1Apte/Adamts9tm1.2Apte
Tg(Prrx1-cre)1Cjt/0 		involves: 129S4/SvJae * C57BL/6 * SJL MGI:5603310
cn4
 		Adamts9tm1.1Apte/Adamts9tm1.1Apte
Tg(Prrx1-cre)1Cjt/0 		involves: C57BL/6 * SJL MGI:5603309


Genotype
MGI:5603200
hm1
Allelic
Composition		 Adamts9tm1.1Apte/Adamts9tm1.1Apte
Genetic
Background		 involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adamts9tm1.1Apte mutation (1 available); any Adamts9 mutation (90 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:213412 )
• mice are viable, fertile and appear grossly normal




Genotype
MGI:5603313
cn2
Allelic
Composition		 Adamts5tm1Dgen/Adamts5tm1Dgen
Adamts9tm1.1Apte/Adamts9tm1.1Apte
Tg(Prrx1-cre)1Cjt/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adamts5tm1Dgen mutation (1 available); any Adamts5 mutation (56 available)
Adamts9tm1.1Apte mutation (1 available); any Adamts9 mutation (90 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
syndactyly ( J:213412 )
• 100% incidence of soft tissue syndactyly
• phenotype is more severe than in either allele alone




Genotype
MGI:5603310
cn3
Allelic
Composition		 Adamts9tm1.1Apte/Adamts9tm1.2Apte
Tg(Prrx1-cre)1Cjt/0
Genetic
Background		 involves: 129S4/SvJae * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adamts9tm1.1Apte mutation (1 available); any Adamts9 mutation (90 available)
Adamts9tm1.2Apte mutation (1 available); any Adamts9 mutation (90 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
syndactyly ( J:213412 )
• present in all forelimbs and all hindlimbs
• mice do not have structural anomalies of bone or patterning anomalies
interdigital webbing ( J:213412 )
• webs are present in all interdigits, although webs do not extend to the tips of digits




Genotype
MGI:5603309
cn4
Allelic
Composition		 Adamts9tm1.1Apte/Adamts9tm1.1Apte
Tg(Prrx1-cre)1Cjt/0
Genetic
Background		 involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adamts9tm1.1Apte mutation (1 available); any Adamts9 mutation (90 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
syndactyly ( J:213412 )
• syndactyly is present in all forelimbs and all hindlimbs
• mice do not have structural anomalies of bone or patterning anomalies
interdigital webbing ( J:213412 )
• persistent webs in all interdigits; although webs do not extend to the tips of digits




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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory