Phenotypes associated with this allele

• Allele Symbol: Bicdl1^{tm2b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 2b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5603351
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Bicdl1^tm2b(EUCOMM)Wtsi/Bicdl1^tm2b(EUCOMM)Wtsi	C57BL/6N-Bicdl1^tm2b(EUCOMM)Wtsi/Bay	MGI:5756837
ht2	Bicdl1^tm2b(EUCOMM)Wtsi/Bicdl1^+	C57BL/6N-Bicdl1^tm2b(EUCOMM)Wtsi/Bay	MGI:5887324

Genotype
MGI:5756837

hm1

• Allelic Composition: Bicdl1^{tm2b(EUCOMM)Wtsi}/Bicdl1^{tm2b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Bicdl1^{tm2b(EUCOMM)Wtsi}/Bay
• Cell Lines: EPD0530_7_B03

Data Sources

IMPC Data for Bicdl1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

decreased vertical activity ( J:211773 )

♀

IMPC - BCM

growth/size/body

enlarged spleen ( J:211773 )

♀

IMPC - BCM

hematopoietic system

abnormal spleen morphology ( J:211773 )

♀

IMPC - BCM

enlarged spleen ( J:211773 )

♀

IMPC - BCM

immune system

abnormal spleen morphology ( J:211773 )

♀

IMPC - BCM

enlarged spleen ( J:211773 )

♀

IMPC - BCM

limbs/digits/tail

short tibia ( J:211773 )

IMPC - BCM

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - BCM

skeleton

short tibia ( J:211773 )

IMPC - BCM

Genotype
MGI:5887324

ht2

• Allelic Composition: Bicdl1^{tm2b(EUCOMM)Wtsi}/Bicdl1⁺
• Genetic Background: C57BL/6N-Bicdl1^{tm2b(EUCOMM)Wtsi}/Bay
• Cell Lines: EPD0530_7_B03

Data Sources

IMPC Data for Bicdl1

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - BCM

cardiovascular system

cardiovascular system phenotype ( J:211773 )

♀

IMPC - BCM

increased heart rate variability ( J:211773 )

♀

IMPC - BCM