All Phenotypes Esr2<tm1.1Ksk> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Esr2^tm1.1Ksk
targeted mutation 1.1, Kenneth S Korach
MGI:5604770

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Esr2^tm1.1Ksk/Esr2^tm1.1Ksk	involves: C57BL/6	MGI:5604773

Allelic Composition	Esr2^tm1.1Ksk/Esr2^tm1.1Ksk
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Esr2^tm1.1Ksk mutation (1 available); any Esr2 mutation (36 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

failure of superovulation ( J:198474 )

• female mice do not respond to exogenous gonadotropin treatments

decreased ovulation rate ( J:198474 )

• inefficient ovulation

reduced female fertility ( J:198474 )

• females are subfertile producing an average of 2.4 pups/litter as compared to 10.1 pups/litter from wild-type

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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