All Phenotypes Pfkfb2<tm1b(KOMP)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pfkfb2^{tm1b(KOMP)Wtsi}
targeted mutation 1b, Wellcome Trust Sanger Institute
MGI:5605741

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pfkfb2^{tm1b(KOMP)Wtsi}/Pfkfb2^{tm1b(KOMP)Wtsi}	C57BL/6N-Pfkfb2^{tm1b(KOMP)Wtsi}/Nju	MGI:5757510

Allelic Composition	Pfkfb2^{tm1b(KOMP)Wtsi}/Pfkfb2^{tm1b(KOMP)Wtsi}
Genetic Background	C57BL/6N-Pfkfb2^{tm1b(KOMP)Wtsi}/Nju
Cell Lines	EPD0308_4_C07

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pfkfb2^{tm1b(KOMP)Wtsi} mutation (0 available); any Pfkfb2 mutation (36 available)

Data Sources

IMPC Data for Pfkfb2

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

thin ventricular wall ( J:211773 )

IMPC - MARC

hematopoietic system

increased basophil cell number ( J:211773 )

IMPC - MARC

increased eosinophil cell number ( J:211773 )

IMPC - MARC

decreased neutrophil cell number ( J:211773 )

IMPC - MARC

increased lymphocyte cell number ( J:211773 )

IMPC - MARC

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

IMPC - MARC

immune system

increased basophil cell number ( J:211773 )

IMPC - MARC

increased eosinophil cell number ( J:211773 )

IMPC - MARC

decreased neutrophil cell number ( J:211773 )

IMPC - MARC

increased lymphocyte cell number ( J:211773 )

IMPC - MARC

vision/eye

abnormal retina morphology ( J:211773 )

IMPC - MARC

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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