Phenotypes associated with this allele

• Allele Symbol: Rad1^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5605756
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rad1^tm1b(KOMP)Wtsi/Rad1^tm1b(KOMP)Wtsi	C57BL/6N-Rad1^tm1b(KOMP)Wtsi/J	MGI:5767780
ht2	Rad1^tm1b(KOMP)Wtsi/Rad1^+	C57BL/6N-Rad1^tm1b(KOMP)Wtsi/J	MGI:5797763

Genotype
MGI:5767780

hm1

• Allelic Composition: Rad1^{tm1b(KOMP)Wtsi}/Rad1^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Rad1^{tm1b(KOMP)Wtsi}/J
• Cell Lines: EPD0241_2_A07

Data Sources

IMPC Data for Rad1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:5797763

ht2

• Allelic Composition: Rad1^{tm1b(KOMP)Wtsi}/Rad1⁺
• Genetic Background: C57BL/6N-Rad1^{tm1b(KOMP)Wtsi}/J
• Cell Lines: EPD0241_2_A07

Data Sources

IMPC Data for Rad1

embryo

abnormal embryo turning ( J:211773 )

IMPC - JAX

hematopoietic system

increased erythrocyte cell number ( J:211773 )

♂

IMPC - JAX

increased hematocrit ( J:211773 )

♂

IMPC - JAX

homeostasis/metabolism

increased circulating bilirubin level ( J:211773 )

♂

IMPC - JAX

increased fasting circulating glucose level ( J:211773 )

♀

IMPC - JAX

decreased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - JAX

decreased circulating iron level ( J:211773 )

♂

IMPC - JAX

skeleton

abnormal bone structure ( J:211773 )

♀

IMPC - JAX

vision/eye

abnormal lens morphology ( J:211773 )

♂

IMPC - JAX