Phenotypes associated with this allele

• Allele Symbol: Pmm2^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5605770
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pmm2^tm1b(EUCOMM)Hmgu/Pmm2^tm1b(EUCOMM)Hmgu	C57BL/6N-Pmm2^tm1b(EUCOMM)Hmgu/Tcp	MGI:5757536
ht2	Pmm2^tm1b(EUCOMM)Hmgu/Pmm2^+	C57BL/6N-Pmm2^tm1b(EUCOMM)Hmgu/Tcp	MGI:5757535

Genotype
MGI:5757536

hm1

• Allelic Composition: Pmm2^{tm1b(EUCOMM)Hmgu}/Pmm2^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Pmm2^{tm1b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0538_8_H04

Data Sources

IMPC Data for Pmm2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - TCP

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - TCP

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

Genotype
MGI:5757535

ht2

• Allelic Composition: Pmm2^{tm1b(EUCOMM)Hmgu}/Pmm2⁺
• Genetic Background: C57BL/6N-Pmm2^{tm1b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0538_8_H04

Data Sources

IMPC Data for Pmm2

homeostasis/metabolism

increased blood urea nitrogen level ( J:211773 )

♀

IMPC - TCP

immune system

enlarged lymph nodes ( J:211773 )

♂

IMPC - TCP