Phenotypes associated with this allele

• Allele Symbol: Prdm12^{tm2b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 2b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5605825
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prdm12^tm2b(EUCOMM)Hmgu/Prdm12^tm2b(EUCOMM)Hmgu	C57BL/6N-Prdm12^tm2b(EUCOMM)Hmgu/Tcp	MGI:6263225
ht2	Prdm12^tm2b(EUCOMM)Hmgu/Prdm12^+	C57BL/6N-Prdm12^tm2b(EUCOMM)Hmgu/Tcp	MGI:5757557

Genotype
MGI:6263225

hm1

• Allelic Composition: Prdm12^{tm2b(EUCOMM)Hmgu}/Prdm12^{tm2b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Prdm12^{tm2b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0689_4_G10

Data Sources

IMPC Data for Prdm12

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

Genotype
MGI:5757557

ht2

• Allelic Composition: Prdm12^{tm2b(EUCOMM)Hmgu}/Prdm12⁺
• Genetic Background: C57BL/6N-Prdm12^{tm2b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0689_4_G10

Data Sources

IMPC Data for Prdm12

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - TCP

decreased locomotor activity ( J:211773 )

♂

IMPC - TCP

cardiovascular system

shortened QRS complex duration ( J:211773 )

♀

IMPC - TCP

embryo

abnormal embryo size ( J:211773 )

IMPC - TCP

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - TCP

homeostasis/metabolism

increased circulating cholesterol level ( J:211773 )

♂

IMPC - TCP