Phenotypes associated with this allele

• Allele Symbol: Grin2b^{tm1e.1(KOMP)Wtsi}
• Allele Name: targeted mutation 1e.1, Wellcome Trust Sanger Institute
• Allele ID: MGI:5605840
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Grin2b^tm1e.1(KOMP)Wtsi/Grin2b^tm1e.1(KOMP)Wtsi	C57BL/6N-Grin2b^tm1e.1(KOMP)Wtsi/Tcp	MGI:6394302
ht2	Grin2b^tm1e.1(KOMP)Wtsi/Grin2b^+	C57BL/6N-Grin2b^tm1e.1(KOMP)Wtsi/Tcp	MGI:5797578

Genotype
MGI:6394302

hm1

• Allelic Composition: Grin2b^{tm1e.1(KOMP)Wtsi}/Grin2b^{tm1e.1(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Grin2b^{tm1e.1(KOMP)Wtsi}/Tcp
• Cell Lines: EPD0852_3_E09

Data Sources

IMPC Data for Grin2b

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:5797578

ht2

• Allelic Composition: Grin2b^{tm1e.1(KOMP)Wtsi}/Grin2b⁺
• Genetic Background: C57BL/6N-Grin2b^{tm1e.1(KOMP)Wtsi}/Tcp
• Cell Lines: EPD0852_3_E09

Data Sources

IMPC Data for Grin2b

behavior/neurological

increased startle reflex ( J:211773 )

♂

IMPC - UCD

decreased locomotor activity ( J:211773 )

♀

IMPC - UCD

cardiovascular system

enlarged heart ( J:211773 )

♂

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - UCD

hematopoietic system

increased mean platelet volume ( J:211773 )

♂

IMPC - UCD