Phenotypes associated with this allele

• Allele Symbol: Rev3l^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5605987
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rev3l^tm1b(EUCOMM)Hmgu/Rev3l^tm1b(EUCOMM)Hmgu	C57BL/6N-Rev3l^tm1b(EUCOMM)Hmgu/J	MGI:6263359
ht2	Rev3l^tm1b(EUCOMM)Hmgu/Rev3l^+	C57BL/6N-Rev3l^tm1b(EUCOMM)Hmgu/J	MGI:6263358

Genotype
MGI:6263359

hm1

• Allelic Composition: Rev3l^{tm1b(EUCOMM)Hmgu}/Rev3l^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Rev3l^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0760_8_D04

Data Sources

IMPC Data for Rev3l

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:6263358

ht2

• Allelic Composition: Rev3l^{tm1b(EUCOMM)Hmgu}/Rev3l⁺
• Genetic Background: C57BL/6N-Rev3l^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0760_8_D04

Data Sources

IMPC Data for Rev3l

behavior/neurological

hyperactivity ( J:211773 )

IMPC - JAX

hematopoietic system

increased mean corpuscular hemoglobin concentration ( J:211773 )

IMPC - JAX

decreased mean corpuscular volume ( J:211773 )

IMPC - JAX

homeostasis/metabolism

decreased circulating creatinine level ( J:211773 )

♀

IMPC - JAX

decreased blood urea nitrogen level ( J:211773 )

♀

IMPC - JAX

vision/eye

cataract ( J:211773 )

♀

IMPC - JAX

abnormal retina morphology ( J:211773 )

IMPC - JAX