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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Susd6tm1.1Geno
targeted mutation 1.1, Genoway
MGI:5606033
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Susd6tm1.1Geno/Susd6tm1.1Geno Not Specified MGI:5606042
cx2
 		Susd6tm1.1Geno/Susd6+
Trp53tm1Tyj/Trp53tm1Tyj 		involves: C57BL/6J MGI:5606044
cx3
 		Susd6tm1.1Geno/Susd6tm1.1Geno
Trp53tm1Tyj/Trp53tm1Tyj 		involves: C57BL/6J MGI:5606045


Genotype
MGI:5606042
hm1
Allelic
Composition		 Susd6tm1.1Geno/Susd6tm1.1Geno
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Susd6tm1.1Geno mutation (0 available); any Susd6 mutation (133 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:210814 )
• viable and fertile; no increased susceptibility to tumor formation




Genotype
MGI:5606044
cx2
Allelic
Composition		 Susd6tm1.1Geno/Susd6+
Trp53tm1Tyj/Trp53tm1Tyj
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Susd6tm1.1Geno mutation (0 available); any Susd6 mutation (133 available)
Trp53tm1Tyj mutation (12 available); any Trp53 mutation (240 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:210814 )
• median survival time of 166 days compared to 190 days in p53-/- mice




Genotype
MGI:5606045
cx3
Allelic
Composition		 Susd6tm1.1Geno/Susd6tm1.1Geno
Trp53tm1Tyj/Trp53tm1Tyj
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Susd6tm1.1Geno mutation (0 available); any Susd6 mutation (133 available)
Trp53tm1Tyj mutation (12 available); any Trp53 mutation (240 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:210814 )
• median survival time of 166 days compared to 190 days in p53-/- mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory