Phenotypes associated with this allele

• Allele Symbol: Tg(Rgs4-EGFP)#Surm
• Allele Name: transgene insertion, D James Surmeier
• Allele ID: MGI:5607413
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Rgs4-EGFP)#Surm/?	involves: C57BL/6J * DBA	MGI:5607427

Genotype
MGI:5607427

tg1

• Allelic Composition: Tg(Rgs4-EGFP)#Surm/?
• Genetic Background: involves: C57BL/6J * DBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal renal plasma flow rate ( J:215588 )

• 18 hours after regional perfusion, blood flow in kidney inner cortex and medulla maintains the same perfusion rate as the sham control, in contrast to a reduction in flow observed in controls

homeostasis/metabolism

abnormal circulating creatinine level ( J:215588 )

• 24 hours post-bilateral ischemic injury serum creatinine levels increase, but not as much as controls

abnormal blood urea nitrogen level ( J:215588 )

• 24 hours post-bilateral ischemic injury BUN levels increase, but not as much as controls

renal/urinary system

abnormal renal tubule morphology ( J:215588 )

• tubular injury is reduced following 25 minute bilateral ischemic injury as compared to controls

abnormal kidney physiology ( J:215588 )

• renal function is preserved following 25 minute bilateral ischemic injury in contrast to controls

abnormal renal plasma flow rate ( J:215588 )

• 18 hours after regional perfusion, blood flow in kidney inner cortex and medulla maintains the same perfusion rate as the sham control, in contrast to a reduction in flow observed in controls