Analysis Tools
immune system
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• mice homozgyous for this mutation exhibit a higher viral titer in the spleen than do control mice five days after infection with a sublethal dose (1.5 x 10e5 PFU/20 g of body weight) of mouse cytomegalovirus (MCMV).
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• following infection with a normally sublethal dose of mouse cytomegalovirus (MCMV), one homozygous mutant mouse died at 4 days post-infection, while three others were sick at 5 days post-infection.
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mortality/aging
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• following infection with a normally sublethal dose of mouse cytomegalovirus (MCMV), one homozygous mutant mouse died at 4 days post-infection, while three others were sick at 5 days post-infection.
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