About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ern2m1Btlr
mutation 1, Bruce Beutler
MGI:5607643
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ern2m1Btlr/Ern2m1Btlr C57BL/6J-Ern2m1Btlr MGI:5607644


Genotype
MGI:5607644
hm1
Allelic
Composition		 Ern2m1Btlr/Ern2m1Btlr
Genetic
Background		 C57BL/6J-Ern2m1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ern2m1Btlr mutation (1 available); any Ern2 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
increased susceptibility to induced colitis ( J:216045 )
• mice homozygous for this mutation exhibit weight loss at day 7 and day 10 after treatment with dextran sulfate sodium (DSS)-containing water, indicative of susceptibility to DSS-induced colitis.

immune system
increased susceptibility to induced colitis ( J:216045 )
• mice homozygous for this mutation exhibit weight loss at day 7 and day 10 after treatment with dextran sulfate sodium (DSS)-containing water, indicative of susceptibility to DSS-induced colitis.




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
07/05/2024
MGI 6.24 		The Jackson Laboratory