Phenotypes associated with this allele

• Allele Symbol: Dnaaf6rt^tm1.2Hmd
• Allele Name: targeted mutation 1.2, Hiroshi Hamada
• Allele ID: MGI:5609303
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dnaaf6rt^tm1.2Hmd/Dnaaf6rt^tm1.2Hmd	involves: ICR	MGI:5609309

Genotype
MGI:5609309

hm1

• Allelic Composition: Dnaaf6rt^tm1.2Hmd/Dnaaf6rt^tm1.2Hmd
• Genetic Background: involves: ICR

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

renal/urinary system

renal/urinary system phenotype ( J:208266 )

N • no kidney cysts

respiratory system

respiratory system phenotype ( J:208266 )

N • no respiratory system abnormalities

growth/size/body

growth/size/body region phenotype ( J:208266 )

N • no situs inversus

reproductive system

reproductive system phenotype ( J:208266 )

♂N • spermatogenesis appears to be normal although there may be regional absence of spermatogenic cells and some accumulation of elongated spermatids

abnormal reproductive system morphology ( J:208266 )

• frequently broken

• other types of motil cilia are normal

abnormal sperm flagellum morphology ( J:208266 )

♂

abnormal sperm axoneme morphology ( J:208266 )

♂ • microtubule organization is disrupted in sperm flagella

♂ • reduced in number or disorganized

thin sperm flagellum ( J:208266 )

♂

short sperm flagellum ( J:208266 )

♂

abnormal male reproductive system physiology ( J:208266 )

♂

asthenozoospermia ( J:208266 )

♂ • sperm are non-motile

male infertility ( J:208266 )

♂ • homozygous males are infertile

cellular

abnormal sperm flagellum morphology ( J:208266 )

♂

abnormal sperm axoneme morphology ( J:208266 )

♂ • microtubule organization is disrupted in sperm flagella

♂ • reduced in number or disorganized

thin sperm flagellum ( J:208266 )

♂

short sperm flagellum ( J:208266 )

♂

asthenozoospermia ( J:208266 )

♂ • sperm are non-motile