Phenotypes associated with this allele

• Allele Symbol: Dpf2^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5609343
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dpf2^tm1b(EUCOMM)Hmgu/Dpf2^tm1b(EUCOMM)Hmgu	C57BL/6N-Dpf2^tm1b(EUCOMM)Hmgu/Tcp	MGI:5767642
ht2	Dpf2^tm1b(EUCOMM)Hmgu/Dpf2^+	C57BL/6N-Dpf2^tm1b(EUCOMM)Hmgu/Tcp	MGI:5797487

Genotype
MGI:5767642

hm1

• Allelic Composition: Dpf2^{tm1b(EUCOMM)Hmgu}/Dpf2^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Dpf2^{tm1b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0687_3_A04

Data Sources

IMPC Data for Dpf2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

♀

IMPC - TCP

craniofacial

abnormal craniofacial morphology ( J:211773 )

IMPC - TCP

embryo

abnormal embryo size ( J:211773 )

IMPC - TCP

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - TCP

homeostasis/metabolism

edema ( J:211773 )

IMPC - TCP

integument

pallor ( J:211773 )

IMPC - TCP

limbs/digits/tail

abnormal limb morphology ( J:211773 )

IMPC - TCP

abnormal tail morphology ( J:211773 )

IMPC - TCP

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

Genotype
MGI:5797487

ht2

• Allelic Composition: Dpf2^{tm1b(EUCOMM)Hmgu}/Dpf2⁺
• Genetic Background: C57BL/6N-Dpf2^{tm1b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0687_3_A04

Data Sources

IMPC Data for Dpf2

endocrine/exocrine glands

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - TCP

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - TCP

reproductive system

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - TCP