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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Leprm6Btlr
mutation 6, Bruce Beutler
MGI:5609704
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Leprm6Btlr/Leprm6Btlr C57BL/6J-Leprm6Btlr MGI:5609706
ht2
 		Leprm6Btlr/Lepr+ C57BL/6J-Leprm6Btlr MGI:5609711


Genotype
MGI:5609706
hm1
Allelic
Composition		 Leprm6Btlr/Leprm6Btlr
Genetic
Background		 C57BL/6J-Leprm6Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Leprm6Btlr mutation (0 available); any Lepr mutation (122 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
increased body weight ( J:216794 )
• mice homozygous for this mutation exhibit a significant increase in body weight compared to wild-type mice.




Genotype
MGI:5609711
ht2
Allelic
Composition		 Leprm6Btlr/Lepr+
Genetic
Background		 C57BL/6J-Leprm6Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Leprm6Btlr mutation (0 available); any Lepr mutation (122 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
increased body weight ( J:216794 )
• mice heterozygous for this mutation exhibit a significantly increased body weight, intermediate between those of homozyous mutant and and wild-type mice, but not significant enough to consider the allele semidominant.




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory