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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Rpgrtm1.1Sgj
targeted mutation 1.1, Samuel G Jacobson
MGI:5610131
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Rpgrtm1.1Sgj/Rpgrtm1.1Sgj involves: 129 * BALB/c MGI:5610133
ot2
Rpgrtm1.1Sgj/Y involves: 129 * BALB/c MGI:5610134


Genotype
MGI:5610133
hm1
Allelic
Composition
Rpgrtm1.1Sgj/Rpgrtm1.1Sgj
Genetic
Background
involves: 129 * BALB/c
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rpgrtm1.1Sgj mutation (0 available); any Rpgr mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• some at 5 to 6 months
• pronounced at 13 months
• inferior thickness is less than superior
• hyperreflective vitreoretinal interface in optical coherence topology scans
• reduced cone electroretinogram at 5 to 7 and 11 to 13 months
• absent cone electroretinogram in older mice
• reduced amplitudes in dark-adapted electroretinogram at 5 to 7 months at higher stimulus intensities
• further reduced amplitudes at 11 to 13 months




Genotype
MGI:5610134
ot2
Allelic
Composition
Rpgrtm1.1Sgj/Y
Genetic
Background
involves: 129 * BALB/c
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rpgrtm1.1Sgj mutation (0 available); any Rpgr mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• some at 5 to 6 months
• pronounced at 13 months
• inferior thickness is less than superior
• hyperreflective vitreoretinal interface in optical coherence topology scans
• reduced cone electroretinogram at 5 to 7 and 11 to 13 months
• absent cone electroretinogram in older mice
• reduced amplitudes in dark-adapted electroretinogram at 5 to 7 months at higher stimulus intensities
• further reduced amplitudes at 11 to 13 months





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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory